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Synthesis of α-D-GalpN(3)-(1-3)-D-GalpN(3): α- and 3-O-selectivity using 3,4-diol acceptors

The motif α-D-GalpNAc-(1-3)-D-GalpNAc is very common in Nature and hence its synthesis highly relevant. The synthesis of its azido precursor has been studied and optimized in terms of steps, yields and selectivity. It has been found that glycosylation of the 3,4-diol acceptor is an advantage over th...

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Detalles Bibliográficos
Autores principales: Glibstrup, Emil, Pedersen, Christian Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244312/
https://www.ncbi.nlm.nih.gov/pubmed/30498530
http://dx.doi.org/10.3762/bjoc.14.258