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Collagen density modulates triple-negative breast cancer cell metabolism through adhesion-mediated contractility

Extracellular matrix (ECM) mechanical properties upregulate cancer invasion, cell contractility, and focal adhesion formation. Alteration in energy metabolism is a known characteristic of cancer cells (i.e., Warburg effect) and modulates cell invasion. There is little evidence to show if collagen de...

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Detalles Bibliográficos
Autores principales: Mah, Emma J., Lefebvre, Austin E. Y. T., McGahey, Gabrielle E., Yee, Albert F., Digman, Michelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244401/
https://www.ncbi.nlm.nih.gov/pubmed/30459440
http://dx.doi.org/10.1038/s41598-018-35381-9