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Collagen density modulates triple-negative breast cancer cell metabolism through adhesion-mediated contractility
Extracellular matrix (ECM) mechanical properties upregulate cancer invasion, cell contractility, and focal adhesion formation. Alteration in energy metabolism is a known characteristic of cancer cells (i.e., Warburg effect) and modulates cell invasion. There is little evidence to show if collagen de...
Autores principales: | Mah, Emma J., Lefebvre, Austin E. Y. T., McGahey, Gabrielle E., Yee, Albert F., Digman, Michelle A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244401/ https://www.ncbi.nlm.nih.gov/pubmed/30459440 http://dx.doi.org/10.1038/s41598-018-35381-9 |
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