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“Liquid Biopsy” of White Matter Hyperintensity in Functionally Normal Elders

Background and Objective: In the aging brain, increased blood-brain barrier (BBB) leakage and white matter hyperintensity (WMH) on MRI are frequently presumed secondary to cerebral small vessel disease (cSVD) or endotheliopathy. We investigate this association in vivo by quantifying protein cargo fr...

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Detalles Bibliográficos
Autores principales: Elahi, Fanny M., Casaletto, Kaitlin B., Altendahl, Marie, Staffaroni, Adam M., Fletcher, Evan, Filshtein, Teresa J., Glymour, Maria M., Miller, Bruce L., Hinman, Jason D., DeCarli, Charles, Goetzl, Edward J., Kramer, Joel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244607/
https://www.ncbi.nlm.nih.gov/pubmed/30483114
http://dx.doi.org/10.3389/fnagi.2018.00343