Cargando…

“Liquid Biopsy” of White Matter Hyperintensity in Functionally Normal Elders

Background and Objective: In the aging brain, increased blood-brain barrier (BBB) leakage and white matter hyperintensity (WMH) on MRI are frequently presumed secondary to cerebral small vessel disease (cSVD) or endotheliopathy. We investigate this association in vivo by quantifying protein cargo fr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Elahi, Fanny M., Casaletto, Kaitlin B., Altendahl, Marie, Staffaroni, Adam M., Fletcher, Evan, Filshtein, Teresa J., Glymour, Maria M., Miller, Bruce L., Hinman, Jason D., DeCarli, Charles, Goetzl, Edward J., Kramer, Joel H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244607/ https://www.ncbi.nlm.nih.gov/pubmed/30483114 http://dx.doi.org/10.3389/fnagi.2018.00343

Ejemplares similares

Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans
por: Elahi, Fanny M., et al.
Publicado: (2021)

Author Correction: Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans
por: Elahi, Fanny M., et al.
Publicado: (2022)

REM sleep is associated with white matter integrity in cognitively healthy, older adults
por: Altendahl, Marie, et al.
Publicado: (2020)

White Matter Hyperintensities: Complex Predictor of Complex Outcomes
por: Karvelas, Nikolaos, et al.
Publicado: (2023)

White matter hyperintensity, neurofilament light chain, and cognitive decline
por: Dhana, Anisa, et al.
Publicado: (2022)

An IL-18-centered inflammatory network as a biomarker for cerebral white matter injury
por: Altendahl, Marie, et al.
Publicado: (2020)

Genome-wide scan in Hispanics highlights candidate loci for brain white matter hyperintensities
por: Beecham, Ashley, et al.
Publicado: (2017)

Staging of amyloid β, t-tau, regional atrophy rates, and cognitive change in a nondemented cohort: Results of serial mediation analyses
por: Fletcher, Evan, et al.
Publicado: (2018)

Association of Subjective Memory Complaints With White Matter Hyperintensities and Cognitive Decline Among Older Adults in Chicago, Illinois
por: Dhana, Anisa, et al.
Publicado: (2022)

White Matter Hyperintensities among Older Adults Are Associated with Futile Increase in Frontal Activation and Functional Connectivity during Spatial Search
por: Lockhart, Samuel N., et al.
Publicado: (2015)

Development and validation of the Uniform Data Set (v3.0) executive function composite score (UDS3‐EF)
por: Staffaroni, Adam M., et al.
Publicado: (2020)

White matter hyperintensity in different migraine subtypes
por: Dobrynina, L. A., et al.
Publicado: (2021)

White matter hyperintensities and neurodegenerative dementias
por: Sassi, Celeste
Publicado: (2019)

Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease
por: Elahi, Fanny M., et al.
Publicado: (2017)

White-matter hyperintensities in first-episode psychosis
por: Zanetti, Marcus V., et al.
Publicado: (2008)

Bullseye's representation of cerebral white matter hyperintensities
por: Sudre, C.H., et al.
Publicado: (2018)

White matter hyperintensities and normal-appearing white matter integrity in the aging brain
por: Maniega, Susana Muñoz, et al.
Publicado: (2015)

White Matter Hyperintensities in Mild Lewy Body Dementia
por: Oppedal, K., et al.
Publicado: (2012)

Validation of Automated White Matter Hyperintensity Segmentation
por: Smart, Sean D., et al.
Publicado: (2011)

Different Types of White Matter Hyperintensities in CADASIL
por: Duchesnay, Edouard, et al.
Publicado: (2018)

Prevalence of white matter hyperintensities increases with age
por: Zhuang, Feng-Juan, et al.
Publicado: (2018)

The Characteristics of White Matter Hyperintensities in Patients With Migraine
por: Chong, Catherine D., et al.
Publicado: (2022)

Semisupervised white matter hyperintensities segmentation on MRI
por: Huang, Fan, et al.
Publicado: (2022)

Venous Collagenosis as Pathogenesis of White Matter Hyperintensity
por: Lahna, David, et al.
Publicado: (2022)

Chronic orofacial pain and white matter hyperintensities
por: Calabria, Elena, et al.
Publicado: (2023)

Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI
por: Yang, Yunju, et al.
Publicado: (2022)

Spatial Signature of White Matter Hyperintensities in Stroke Patients
por: Schirmer, Markus D., et al.
Publicado: (2019)

Tract-defined regional white matter hyperintensities and memory
por: Rizvi, Batool, et al.
Publicado: (2019)

Associations between White Matter Hyperintensities and β Amyloid on Integrity of Projection, Association, and Limbic Fiber Tracts Measured with Diffusion Tensor MRI
por: Chao, Linda L., et al.
Publicado: (2013)

In vivo myelin imaging and tissue microstructure in white matter hyperintensities and perilesional white matter
por: Ferris, Jennifer K., et al.
Publicado: (2022)

Structural neuroimaging in Alzheimer's disease: do white matter hyperintensities matter?
por: Brickman, Adam M., et al.
Publicado: (2009)

Instrumental validation of free water, peak‐width of skeletonized mean diffusivity, and white matter hyperintensities: MarkVCID neuroimaging kits
por: Maillard, Pauline, et al.
Publicado: (2022)

Walking energetics and white matter hyperintensities in mid‐to‐late adulthood
por: Dougherty, Ryan J., et al.
Publicado: (2023)

Genetic Architecture of White Matter Hyperintensities Differs in Hypertensive and Nonhypertensive Ischemic Stroke
por: Adib-Samii, Poneh, et al.
Publicado: (2015)

White matter hyperintensities are associated with disproportionate progressive hippocampal atrophy
por: Fiford, Cassidy M., et al.
Publicado: (2017)

Circulating metabolites are associated with brain atrophy and white matter hyperintensities
por: de Leeuw, Francisca A., et al.
Publicado: (2020)

Contribution of white matter hyperintensities to ventricular enlargement in older adults
por: Jochems, Angela C.C., et al.
Publicado: (2022)

Characterization of White Matter Hyperintensities in Large-Scale MRI-Studies
por: Frey, Benedikt M., et al.
Publicado: (2019)

Aortic hemodynamics and white matter hyperintensities in normotensive postmenopausal women
por: Barnes, Jill N., et al.
Publicado: (2017)

Mild Motor Signs Matter in Typical Brain Aging: The Value of the UPDRS Score Within a Functionally Intact Cohort of Older Adults
por: Zitser, Jennifer, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8u0ej4u52otp3l5ss8kpr1ojba