Building a Hepatitis C Clinical Program: Strategies to Optimize Outcomes

PURPOSE OF REVIEW: An increasing number of specialists and non-specialists are developing clinical programs to treat and cure hepatitis C virus (HCV). The goal of this paper is to evaluate and describe optimal strategies to improve outcomes related to HCV care delivery. RECENT FINDINGS: Screening an...

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Autores principales: Zuckerman, Autumn, Carver, Alicia, Chastain, Cody A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244618/
https://www.ncbi.nlm.nih.gov/pubmed/30524209
http://dx.doi.org/10.1007/s40506-018-0177-5
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author Zuckerman, Autumn
Carver, Alicia
Chastain, Cody A.
author_facet Zuckerman, Autumn
Carver, Alicia
Chastain, Cody A.
author_sort Zuckerman, Autumn
collection PubMed
description PURPOSE OF REVIEW: An increasing number of specialists and non-specialists are developing clinical programs to treat and cure hepatitis C virus (HCV). The goal of this paper is to evaluate and describe optimal strategies to improve outcomes related to HCV care delivery. RECENT FINDINGS: Screening and diagnosis of HCV should be guided by established recommendations. Given the recognized disparity in HCV diagnosis and linkage to care, a multi-modal approach involving care coordination and technology resources should be used to improve patient engagement. Access to HCV treatment may be optimized through systematic documentation, prior authorization, and appeal processes. Treatment monitoring should emphasize medication adherence, side effect and drug interaction management, as well as elimination of practical barriers. Finally, post-treatment engagement to promote liver health and reduce the risk of complications or reinfection maximizes the benefit of HCV treatment. SUMMARY: The landscape of HCV treatment has evolved from a specialist-driven model with few patients qualifying for treatment to an opportunity for non-specialists and other providers to provide curative therapies in most patients. Innovative practice models that employ a multidisciplinary approach will likely improve screening, diagnosis, engagement, and treatment outcomes.
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spelling pubmed-62446182018-12-04 Building a Hepatitis C Clinical Program: Strategies to Optimize Outcomes Zuckerman, Autumn Carver, Alicia Chastain, Cody A. Curr Treat Options Infect Dis Hepatitis C (J Raybould, Section Editor) PURPOSE OF REVIEW: An increasing number of specialists and non-specialists are developing clinical programs to treat and cure hepatitis C virus (HCV). The goal of this paper is to evaluate and describe optimal strategies to improve outcomes related to HCV care delivery. RECENT FINDINGS: Screening and diagnosis of HCV should be guided by established recommendations. Given the recognized disparity in HCV diagnosis and linkage to care, a multi-modal approach involving care coordination and technology resources should be used to improve patient engagement. Access to HCV treatment may be optimized through systematic documentation, prior authorization, and appeal processes. Treatment monitoring should emphasize medication adherence, side effect and drug interaction management, as well as elimination of practical barriers. Finally, post-treatment engagement to promote liver health and reduce the risk of complications or reinfection maximizes the benefit of HCV treatment. SUMMARY: The landscape of HCV treatment has evolved from a specialist-driven model with few patients qualifying for treatment to an opportunity for non-specialists and other providers to provide curative therapies in most patients. Innovative practice models that employ a multidisciplinary approach will likely improve screening, diagnosis, engagement, and treatment outcomes. Springer US 2018-10-18 2018 /pmc/articles/PMC6244618/ /pubmed/30524209 http://dx.doi.org/10.1007/s40506-018-0177-5 Text en © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Hepatitis C (J Raybould, Section Editor)
Zuckerman, Autumn
Carver, Alicia
Chastain, Cody A.
Building a Hepatitis C Clinical Program: Strategies to Optimize Outcomes
title Building a Hepatitis C Clinical Program: Strategies to Optimize Outcomes
title_full Building a Hepatitis C Clinical Program: Strategies to Optimize Outcomes
title_fullStr Building a Hepatitis C Clinical Program: Strategies to Optimize Outcomes
title_full_unstemmed Building a Hepatitis C Clinical Program: Strategies to Optimize Outcomes
title_short Building a Hepatitis C Clinical Program: Strategies to Optimize Outcomes
title_sort building a hepatitis c clinical program: strategies to optimize outcomes
topic Hepatitis C (J Raybould, Section Editor)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244618/
https://www.ncbi.nlm.nih.gov/pubmed/30524209
http://dx.doi.org/10.1007/s40506-018-0177-5
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