Elevated monocyte-specific type I interferon signalling correlates positively with cardiac healing in myocardial infarct patients but interferon alpha application deteriorates myocardial healing in rats

Monocytes are involved in adverse left ventricular (LV) remodelling following myocardial infarction (MI). To provide therapeutic opportunities we aimed to identify gene transcripts in monocytes that relate to post-MI healing and evaluated intervention with the observed gene activity in a rat MI mode...

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Detalles Bibliográficos
Autores principales: ter Horst, Ellis N., Krijnen, Paul A. J., Hakimzadeh, Nazanin, Robbers, Lourens F. H. J., Hirsch, Alexander, Nijveldt, Robin, Lommerse, Ingrid, Fontijn, Ruud D., Meinster, Elisa, Delewi, Ronak, van Royen, Niels, Zijlstra, Felix, van Rossum, Albert C., van der Schoot, C. Ellen, van der Pouw Kraan, Tineke C. T. M., Horrevoets, Anton J., van der Laan, Anja M., Niessen, Hans W. M., Piek, Jan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244641/
https://www.ncbi.nlm.nih.gov/pubmed/30443679
http://dx.doi.org/10.1007/s00395-018-0709-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244641/
https://www.ncbi.nlm.nih.gov/pubmed/30443679
http://dx.doi.org/10.1007/s00395-018-0709-7

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