The concept of the okadaic acid class of tumor promoters is revived in endogenous protein inhibitors of protein phosphatase 2A, SET and CIP2A, in human cancers

PURPOSE: The okadaic acid class of tumor promoters, which are inhibitors of protein phosphatases 1 and 2A (PP1 and PP2A), induced tumor promotion in mouse skin, rat glandular stomach, and rat liver. Endogenous protein inhibitors of PP2A, SET and CIP2A, were up-regulated in various human cancers, so...

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Detalles Bibliográficos
Autores principales: Fujiki, Hirota, Sueoka, Eisaburo, Watanabe, Tatsuro, Suganuma, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Review – Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244643/
https://www.ncbi.nlm.nih.gov/pubmed/30341686
http://dx.doi.org/10.1007/s00432-018-2765-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244643/
https://www.ncbi.nlm.nih.gov/pubmed/30341686
http://dx.doi.org/10.1007/s00432-018-2765-7

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