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Morin decreases galectin-3 expression and sensitizes ovarian cancer cells to cisplatin

PURPOSE: This study aimed at evaluating whether morin (a natural flavonoid and a known inhibitor of NF-κB) can sensitize ovarian cancer cells to cisplatin by decreasing the expression of galectin-3, which is an anti-apoptotic protein regulated by NF-κB transcription factor. METHODS: To assess the po...

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Detalles Bibliográficos
Autores principales: Bieg, Dominik, Sypniewski, Daniel, Nowak, Ewa, Bednarek, Ilona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244704/
https://www.ncbi.nlm.nih.gov/pubmed/30267152
http://dx.doi.org/10.1007/s00404-018-4912-4