Effect of Multiple Doses of Omeprazole on the Pharmacokinetics, Safety, and Tolerability of Roxadustat in Healthy Subjects

BACKGROUND AND OBJECTIVES: Roxadustat is an orally active hypoxia-inducible factor prolyl hydroxylase inhibitor for the treatment of anemia in chronic kidney disease. This study investigated the effect of multiple daily oral doses of omeprazole on the pharmacokinetics, safety, and tolerability of a...

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Detalles Bibliográficos
Autores principales: Groenendaal-van de Meent, Dorien, den Adel, Martin, van Dijk, Jan, Barroso-Fernandez, Begona, El Galta, Rachid, Golor, Georg, Schaddelee, Marloes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244714/
https://www.ncbi.nlm.nih.gov/pubmed/29752643
http://dx.doi.org/10.1007/s13318-018-0480-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244714/
https://www.ncbi.nlm.nih.gov/pubmed/29752643
http://dx.doi.org/10.1007/s13318-018-0480-z

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