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Drug-induced expression of EpCAM contributes to therapy resistance in esophageal adenocarcinoma

BACKGROUND: With a less than 5% overall survival rate, esophageal adenocarcinoma (EAC) is one of the leading causes of death in the United States. Epithelial cell adhesion molecule (EpCAM) is a cancer stem cell (CSC) marker that is expressed in various epithelial carcinomas, including EAC. Accumulat...

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Detalles Bibliográficos
Autores principales: Sun, Xuan, Martin, Robert C. G., Zheng, Qianqian, Farmer, Russell, Pandit, Harshul, Li, Xuanyi, Jacob, Kevin, Suo, Jian, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244739/
https://www.ncbi.nlm.nih.gov/pubmed/30116994
http://dx.doi.org/10.1007/s13402-018-0399-z