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Absorption, Distribution, Metabolism, and Excretion of the Novel Helicase-Primase Inhibitor, Amenamevir (ASP2151), in Rodents

BACKGROUND AND OBJECTIVES: The helicase-primase inhibitor amenamevir (ASP2151) is a novel therapeutic agent which has been approved for the treatment of herpes zoster. The present study examined the pharmacokinetic profile of amenamevir in rodents and compared it with data from the literature of pas...

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Detalles Bibliográficos
Autores principales: Ohtsu, Yoshiaki, Susaki, Yoko, Noguchi, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244745/
https://www.ncbi.nlm.nih.gov/pubmed/29748821
http://dx.doi.org/10.1007/s13318-018-0481-y