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EGb761 improves the cognitive function of elderly db/db(−/−) diabetic mice by regulating the beclin-1 and NF-κB signaling pathways

To assess whether EGb761 could protect elderly diabetic mice with cognitive disorders and explore the role of beclin-1-mediated autophagy in these protective effects. Two-month-old male db/db(−/−) mice and wild-type C57/BL6 mice were randomly divided into six groups: db/db(−/−) control, db/db(−/−) 5...

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Detalles Bibliográficos
Autores principales: Guan, Zhu-Fei, Zhang, Xiao-Ming, Tao, Ying-Hong, Zhang, Yu, Huang, Yan-Yan, Chen, Gang, Tang, Wei-Jun, Ji, Gang, Guo, Qi-Lin, Liu, Ming, Zhang, Qian, Wang, Na-Na, Yu, Zhong-Yu, Hao-Yang, Wu, Guo-Feng, Tang, Zhou-Ping, Du, Zun-Guo, Shang, Xi-Liang, Liu, Ying-Chao, Mei, Guang-Hai, Guo, Jing-Chun, Zhou, Hou-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244769/
https://www.ncbi.nlm.nih.gov/pubmed/30187180
http://dx.doi.org/10.1007/s11011-018-0295-2