Cargando…

EGb761 improves the cognitive function of elderly db/db(−/−) diabetic mice by regulating the beclin-1 and NF-κB signaling pathways

To assess whether EGb761 could protect elderly diabetic mice with cognitive disorders and explore the role of beclin-1-mediated autophagy in these protective effects. Two-month-old male db/db(−/−) mice and wild-type C57/BL6 mice were randomly divided into six groups: db/db(−/−) control, db/db(−/−) 5...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guan, Zhu-Fei, Zhang, Xiao-Ming, Tao, Ying-Hong, Zhang, Yu, Huang, Yan-Yan, Chen, Gang, Tang, Wei-Jun, Ji, Gang, Guo, Qi-Lin, Liu, Ming, Zhang, Qian, Wang, Na-Na, Yu, Zhong-Yu, Hao-Yang, Wu, Guo-Feng, Tang, Zhou-Ping, Du, Zun-Guo, Shang, Xi-Liang, Liu, Ying-Chao, Mei, Guang-Hai, Guo, Jing-Chun, Zhou, Hou-Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244769/ https://www.ncbi.nlm.nih.gov/pubmed/30187180 http://dx.doi.org/10.1007/s11011-018-0295-2

Ejemplares similares

9-PAHSA Improves Cardiovascular Complications by Promoting Autophagic Flux and Reducing Myocardial Hypertrophy in Db/Db Mice
por: Wang, Yan-Mei, et al.
Publicado: (2021)

Corrigendum: 9-PAHSA Improves Cardiovascular Complications by Promoting Autophagic Flux and Reducing Myocardial Hypertrophy in Db/Db Mice
por: Wang, Yan-Mei, et al.
Publicado: (2022)

Antiapoptotic Effects of EGb 761
por: Serrano-García, Norma, et al.
Publicado: (2013)

EGb761 protects motoneurons against avulsion-induced oxidative stress in rats
por: Cheng, Xiao, et al.
Publicado: (2010)

Beclin-1- mediated autophagy may be involved in the elderly cognitive and affective disorders in streptozotocin-induced diabetic mice
por: Guan, Zhu-Fei, et al.
Publicado: (2016)

Recombinant fusion protein by lysozyme and antibacterial peptide enhances ischemic wound healing via angiogenesis and reduction of inflammation in diabetic db/db mice
por: Li, Wei, et al.
Publicado: (2021)

Ginkgo Biloba Extract EGB761 Protects against Aging-Associated Diastolic Dysfunction in Cardiomyocytes of D-Galactose-Induced Aging Rat
por: Liu, Jing, et al.
Publicado: (2012)

Protective effect of Ginkgo biloba leaves extract, EGb761, on myocardium injury in ischemia reperfusion rats via regulation of TLR-4/NF-κB signaling pathway
por: Tang, Yuping, et al.
Publicado: (2017)

The Effect of Ginkgo Biloba (EGb 761) on Epileptic Activity in Rabbits
por: Ivetic, Vesna, et al.
Publicado: (2008)

A Detailed View on the Proanthocyanidins in Ginkgo Extract EGb 761
por: Kulić, Žarko, et al.
Publicado: (2021)

Artemether Regulates Metaflammation to Improve Glycolipid Metabolism in db/db Mice
por: Fu, Wei, et al.
Publicado: (2020)

Hydrogen sulfide improves vessel formation of the ischemic adductor muscle and wound healing in diabetic db/db mice
por: Wang, Guo-Guang, et al.
Publicado: (2019)

Ginkgo biloba extract EGb 761–induced upregulation of LincRNA-p21 inhibits colorectal cancer metastasis by associating with EZH2
por: Liu, Tingting, et al.
Publicado: (2017)

Antidiabetic and Antiobesity Effects of Artemether in db/db Mice
por: Guo, Yu, et al.
Publicado: (2018)

EGB761 ameliorates chronic cerebral hypoperfusion-induced cognitive dysfunction and synaptic plasticity impairment
por: Yao, Zhao-Hui, et al.
Publicado: (2021)

Effect of Ginkgo biloba Extract EGb761 on Hippocampal Neuronal Injury and Carbonyl Stress of D-Gal-Induced Aging Rats
por: Li, Juan, et al.
Publicado: (2019)

CoMutDB: the landscape of somatic mutation co-occurrence in cancers
por: Jiang, Limin, et al.
Publicado: (2022)

Apoptosis Induced by Ginkgo biloba (EGb761) in Melanoma Cells Is Mcl-1-Dependent
por: Wang, Yufang, et al.
Publicado: (2015)

Stem Cell Replacement Improves Expression of SMP30 in db/db Mice
por: Li, Ming, et al.
Publicado: (2015)

Dioscin Reduces Vascular Damage in the Retina of db/db Mice by Inhibiting the VEGFA Signaling Pathway
por: Wang, Jun, et al.
Publicado: (2022)

Anti-Diabetic Activities of Jiaotaiwan in db/db Mice by Augmentation of AMPK Protein Activity and Upregulation of GLUT4 Expression
por: Hu, Na, et al.
Publicado: (2013)

Berberine alleviates hyperglycemia by targeting hepatic glucokinase in diabetic db/db mice
por: Li, Meng, et al.
Publicado: (2019)

Adiponectin retards the progression of diabetic nephropathy in db/db mice by counteracting angiotensin II
por: Guo, Xiaohua, et al.
Publicado: (2014)

Ginsenoside Rb1 ameliorates liver fat accumulation by upregulating perilipin expression in adipose tissue of db/db obese mice
por: Yu, Xizhong, et al.
Publicado: (2015)

Mild Cognitive Impairment and Mild Dementia: The Role of Ginkgo biloba (EGb 761(®))
por: Tomino, Carlo, et al.
Publicado: (2021)

Liraglutide downregulates hepatic LDL receptor and PCSK9 expression in HepG2 cells and db/db mice through a HNF-1a dependent mechanism
por: Yang, Sheng-Hua, et al.
Publicado: (2018)

Effects of Ginkgo biloba extract EGb761 on neural differentiation of stem cells offer new hope for neurological disease treatment
por: Ren, Chao, et al.
Publicado: (2019)

Chlorogenic acid improves glucose tolerance, lipid metabolism, inflammation and microbiota composition in diabetic db/db mice
por: Yan, Yongwang, et al.
Publicado: (2022)

PPARγ Agonist Rosiglitazone Suppresses Renal mPGES-1/PGE2 Pathway in db/db Mice
por: Sun, Ying, et al.
Publicado: (2013)

Irbesartan Ameliorates Diabetic Nephropathy by Suppressing the RANKL-RANK-NF-κB Pathway in Type 2 Diabetic db/db Mice
por: Chen, Xiao-Wen, et al.
Publicado: (2016)

Schistosoma japonicum Soluble Egg Antigen Protects Against Type 2 Diabetes in Lepr(db/db) Mice by Enhancing Regulatory T Cells and Th2 Cytokines
por: Tang, Chun-lian, et al.
Publicado: (2019)

eccDB: a comprehensive repository for eccDNA-mediated chromatin contacts in multi-species
por: Yang, Min, et al.
Publicado: (2023)

Effects of phlorizin on diabetic retinopathy according to isobaric tags for relative and absolute quantification–based proteomics in db/db mice
por: Zhang, Shi-yang, et al.
Publicado: (2013)

Ginkgo Biloba Extract EGb 761 Alleviates Hepatic Fibrosis and Sinusoidal Microcirculation Disturbance in Patients with Chronic Hepatitis B
por: Zhang, Cai Fen, et al.
Publicado: (2008)

Active Time-Restricted Feeding Improved Sleep-Wake Cycle in db/db Mice
por: Hou, Tianfei, et al.
Publicado: (2019)

The Ginkgo biloba Extract EGb 761 Modulates Proteasome Activity and Polyglutamine Protein Aggregation
por: Stark, Marcel, et al.
Publicado: (2014)

Preventive Effects of Ginkgo-Extract EGb 761(®) on Noise Trauma-Induced Cochlear Synaptopathy
por: Tziridis, Konstantin, et al.
Publicado: (2022)

Ginkgo biloba leaf extract EGb 761(®) as a paragon of the product by process concept
por: Kulić, Žarko, et al.
Publicado: (2022)

Corrigendum to “Irbesartan Ameliorates Diabetic Nephropathy by Suppressing the RANKL-RANK-NF-κB Pathway in Type 2 Diabetic db/db Mice”
por: Chen, Xiao-Wen, et al.
Publicado: (2016)

Epigallocatechin-3-gallate Attenuates Renal Damage by Suppressing Oxidative Stress in Diabetic db/db Mice
por: Yang, Xiu Hong, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_b3rmnhuaqaachmef18vtvtp30g