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Mitochondrial alterations accompanied by oxidative stress conditions in skin fibroblasts of Huntington’s disease patients

Huntington disease (HD) is an autosomal dominant neurodegenerative disorder manifesting as progressive impairment of motor function and different neuropsychiatric symptoms caused by an expansion of CAG repeats in huntingtin gene (HTT). Mitochondrial dysfunction and bioenergetic defects can contribut...

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Detalles Bibliográficos
Autores principales: Jędrak, Paulina, Mozolewski, Paweł, Węgrzyn, Grzegorz, Więckowski, Mariusz R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244791/
https://www.ncbi.nlm.nih.gov/pubmed/30120672
http://dx.doi.org/10.1007/s11011-018-0308-1