MC1568 improves insulin secretion in islets from type 2 diabetes patients and rescues β-cell dysfunction caused by Hdac7 upregulation

AIMS: It has in recent years been established that epigenetic changes contribute to β-cell dysfunction and type 2 diabetes (T2D). For example, we have showed that the expression of histone deacetylase 7 (HDAC7) is increased in pancreatic islets of individuals with T2D and that increased levels of Hd...

Descripción completa

Detalles Bibliográficos
Autores principales: Daneshpajooh, Mahboubeh, Eliasson, Lena, Bacos, Karl, Ling, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244806/
https://www.ncbi.nlm.nih.gov/pubmed/30088095
http://dx.doi.org/10.1007/s00592-018-1201-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244806/
https://www.ncbi.nlm.nih.gov/pubmed/30088095
http://dx.doi.org/10.1007/s00592-018-1201-4

Ejemplares similares