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The FOXP3 rs3761547 Gene Polymorphism in Multiple Sclerosis as a Male-Specific Risk Factor

The FOXP3 gene encodes a transcription factor and is predominantly expressed in the CD4(+)CD25(+) regulatory T cells which plays a pivotal role in the maintenance of immune homeostasis. The defect of FOXP3 gene may provide a critical link between autoimmunity and immune deficiency. The purpose of ou...

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Detalles Bibliográficos
Autores principales: Wawrusiewicz-Kurylonek, Natalia, Chorąży, Monika, Posmyk, Renata, Zajkowska, Olga, Zajkowska, Agata, Krętowski, Adam Jacek, Tarasiuk, Joanna, Kochanowicz, Jan, Kułakowska, Alina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244921/
https://www.ncbi.nlm.nih.gov/pubmed/30229436
http://dx.doi.org/10.1007/s12017-018-8512-z