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The FOXP3 rs3761547 Gene Polymorphism in Multiple Sclerosis as a Male-Specific Risk Factor
The FOXP3 gene encodes a transcription factor and is predominantly expressed in the CD4(+)CD25(+) regulatory T cells which plays a pivotal role in the maintenance of immune homeostasis. The defect of FOXP3 gene may provide a critical link between autoimmunity and immune deficiency. The purpose of ou...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244921/ https://www.ncbi.nlm.nih.gov/pubmed/30229436 http://dx.doi.org/10.1007/s12017-018-8512-z |