Novel Prodrugs for Targeting Diagnostic and Therapeutic Radionuclides to Solid Tumors

Most cancer therapeutics (chemo, radiation, antibody-based, anti-angiogenic) are at best partially and/or temporarily effective. In general, the causes for failure can be summarized as: (i) poor diffusion and/or nonuniform distribution of drug/prodrug molecules in solid tumors; (ii) high drug concen...

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Detalles Bibliográficos
Autores principales: Kassis, Amin I., Korideck, Houari, Wang, Ketai, Pospisil, Pavel, Adelstein, S. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244955/
https://www.ncbi.nlm.nih.gov/pubmed/18305426
http://dx.doi.org/10.3390/molecules13020391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244955/
https://www.ncbi.nlm.nih.gov/pubmed/18305426
http://dx.doi.org/10.3390/molecules13020391

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