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Novel Prodrugs for Targeting Diagnostic and Therapeutic Radionuclides to Solid Tumors
Most cancer therapeutics (chemo, radiation, antibody-based, anti-angiogenic) are at best partially and/or temporarily effective. In general, the causes for failure can be summarized as: (i) poor diffusion and/or nonuniform distribution of drug/prodrug molecules in solid tumors; (ii) high drug concen...
Autores principales: | Kassis, Amin I., Korideck, Houari, Wang, Ketai, Pospisil, Pavel, Adelstein, S. James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244955/ https://www.ncbi.nlm.nih.gov/pubmed/18305426 http://dx.doi.org/10.3390/molecules13020391 |
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