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The molecular mechanism of anticancer action of novel octahydropyrazino[2,1-a:5,4-a′]diisoquinoline derivatives in human gastric cancer cells

Objective The aim of the current study was to examine the anticancer activity and the detailed mechanism of novel diisoquinoline derivatives in human gastric cancer cells (AGS). Methods The viability of AGS cells was measured by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assa...

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Detalles Bibliográficos
Autores principales: Pawłowska, Natalia, Gornowicz, Agnieszka, Bielawska, Anna, Surażyński, Arkadiusz, Szymanowska, Anna, Czarnomysy, Robert, Bielawski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244973/
https://www.ncbi.nlm.nih.gov/pubmed/29549610
http://dx.doi.org/10.1007/s10637-018-0584-y