Ferroquine, an Ingenious Antimalarial Drug –Thoughts on the Mechanism of Action

Ferroquine (FQ or SR97193) is a novel antimalarial drug candidate, currently in development at Sanofi-Aventis. In contrast to conventional drugs, FQ is the first organometallic drug: a ferrocenyl group covalently flanked by a 4-aminoquinoline and a basic alkylamine. FQ is able to overcome the CQ res...

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Detalles Bibliográficos
Autores principales: Dubar, Faustine, Khalife, Jamal, Brocard, Jacques, Dive, Daniel, Biot, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245066/
https://www.ncbi.nlm.nih.gov/pubmed/19020475
http://dx.doi.org/10.3390/molecules13112900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245066/
https://www.ncbi.nlm.nih.gov/pubmed/19020475
http://dx.doi.org/10.3390/molecules13112900

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