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Ferroquine, an Ingenious Antimalarial Drug –Thoughts on the Mechanism of Action
Ferroquine (FQ or SR97193) is a novel antimalarial drug candidate, currently in development at Sanofi-Aventis. In contrast to conventional drugs, FQ is the first organometallic drug: a ferrocenyl group covalently flanked by a 4-aminoquinoline and a basic alkylamine. FQ is able to overcome the CQ res...
Autores principales: | Dubar, Faustine, Khalife, Jamal, Brocard, Jacques, Dive, Daniel, Biot, Christophe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245066/ https://www.ncbi.nlm.nih.gov/pubmed/19020475 http://dx.doi.org/10.3390/molecules13112900 |
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