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Synthesis of New N-Arylpyrimidin-2-amine Derivatives Using a Palladium Catalyst

New N-aryl-4-(pyridin-3-yl)pyrimidin-2-amine derivatives were synthesized from the corresponding amines, applying optimized Buchwald-Hartwig amination conditions using dichlorobis(triphenylphosphine)Pd(II), xantphos and sodium tert-butoxide in refluxing toluene under a nitrogen atmosphere. The targe...

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Detalles Bibliográficos
Autores principales: El-Deeb, Ibrahim Mustafa, Ryu, Jae Chun, Lee, So Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245071/
https://www.ncbi.nlm.nih.gov/pubmed/18463584
http://dx.doi.org/10.3390/molecules13040818