Cargando…

Effects of Anonaine on Dopamine Biosynthesis and l-DOPA-Induced Cytotoxicity in PC12 Cells

The effects of anonaine, an aporphine isoquinoline alkaloid, on dopamine biosynthesis and l-DOPA-induced cytotoxicity in PC12 cells were investigated. Anonaine at concentration ranges of 0.01-0.2 μM showed a significant inhibition of dopamine content at 24 h, with an IC(50) value of 0.05 μM. Anonain...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Jae Joon, Jin, Chun Mei, Kim, Young Kyoon, Ryu, Shi Yong, Lim, Sung Cil, Lee, Myung Koo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2008
Materias:	Full Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245076/ https://www.ncbi.nlm.nih.gov/pubmed/18305432 http://dx.doi.org/10.3390/molecules13020475

Ejemplares similares

The Pharmacological Activities of (−)-Anonaine
por: Li, Hsing-Tan, et al.
Publicado: (2013)

Epigallocatechin gallate attenuates L-DOPA-induced apoptosis in rat PC12 cells
por: Lee, Myung-Yul, et al.
Publicado: (2013)

1-O-Hexyl-2,3,5-Trimethylhydroquinone Ameliorates l-DOPA-Induced Cytotoxicity in PC12 Cells
por: Park, Hyun Jin, et al.
Publicado: (2019)

The Molecular Pages of the mesotelencephalic dopamine consortium (DopaNet)
por: Le Novère, Nicolas, et al.
Publicado: (2004)

DOPA Homeostasis by Dopamine: A Control-Theoretic View
por: Kleppe, Rune, et al.
Publicado: (2021)

Carvacrol and Thymol Attenuate Cytotoxicity Induced by Amyloid β(25-35 )via Activating Protein Kinase C and Inhibiting Oxidative Stress in PC12 Cells
por: Azizi, Zahra, et al.
Publicado: (2020)

Dopamine-Depleted Dopamine Transporter Knockout (DDD) Mice: Dyskinesia with L-DOPA and Dopamine D1 Agonists
por: Pogorelov, Vladimir M., et al.
Publicado: (2023)

Iron Oxide Nanoparticles: Biosynthesis, Magnetic Behavior, Cytotoxic Effect
por: Miri, Abdolhossein, et al.
Publicado: (2021)

L-dopa-induced dyskinesia: beyond an excessive dopamine tone in the striatum
por: Porras, Gregory, et al.
Publicado: (2014)

How does conserved dopamine neurotrophic factor protect against and rescue neurodegeneration of PC12 cells?
por: Mei, Jia-ming, et al.
Publicado: (2017)

Alterations in the intrinsic properties of striatal cholinergic interneurons after dopamine lesion and chronic L-DOPA
por: Choi, Se Joon, et al.
Publicado: (2020)

Raman Characterization of Fungal DHN and DOPA Melanin Biosynthesis Pathways
por: Strycker, Benjamin D., et al.
Publicado: (2021)

Evaluation of Anticancer and Cytotoxic Effects of Genistein on PC3 Prostate Cell Line under Three-Dimensional Culture Medium
por: Khamesi, Seyedeh Masoumeh, et al.
Publicado: (2022)

Presynaptic dopamine function measured with [(18)F]fluorodopa and L-DOPA effects on impulsive choice
por: Petzold, Johannes, et al.
Publicado: (2019)

The Vasomotor Response to Dopamine Is Altered in the Rat Model of l‐dopa‐Induced Dyskinesia
por: Booth, Samuel, et al.
Publicado: (2020)

Enantioselective Cytotoxicity Profile of o,p’-DDT in PC 12 Cells
por: Zhao, Meirong, et al.
Publicado: (2012)

Identification of biochemical and cytotoxic markers in cocaine treated PC12 cells
por: Badisa, Ramesh B., et al.
Publicado: (2018)

Cytotoxic Effects of Coated Gold Nanoparticles on PC12 Cancer Cell
por: Zare Marzouni, Hadi, et al.
Publicado: (2018)

The Dopamine Augmenter L-DOPA Does Not Affect Positive Mood in Healthy Human Volunteers
por: Liggins, John, et al.
Publicado: (2012)

Dopamine Transporter Binding Is Unaffected by L-DOPA Administration in Normal and MPTP-Treated Monkeys
por: Fernagut, Pierre-Olivier, et al.
Publicado: (2010)

Immobilization of Bone Morphogenetic Protein on DOPA- or Dopamine-Treated Titanium Surfaces to Enhance Osseointegration
por: Kang, Jeonghwa, et al.
Publicado: (2013)

Combination Treatment of Icariin and L-DOPA Against 6-OHDA-Lesioned Dopamine Neurotoxicity
por: Lu, Di-Sheng, et al.
Publicado: (2018)

Polymorphisms of Dopamine Receptor Genes and Risk of L-Dopa–Induced Dyskinesia in Parkinson’s Disease
por: Comi, Cristoforo, et al.
Publicado: (2017)

Dopamine D3 Receptor Plasticity in Parkinson’s Disease and L-DOPA-Induced Dyskinesia
por: Lanza, Kathryn, et al.
Publicado: (2021)

Antiradical Activity of Dopamine, L-DOPA, Adrenaline, and Noradrenaline in Water/Methanol and in Liposomal Systems
por: Jodko-Piórecka, Katarzyna, et al.
Publicado: (2021)

Effect of acute millimeter wave exposure on dopamine metabolism of NGF-treated PC12 cells
por: Haas, Alexis J., et al.
Publicado: (2017)

Elevation of gene expression of calcineurin, calmodulin and calsyntenin in oxidative stress induced PC12 cells
por: Aravind, P., et al.
Publicado: (2019)

Simultaneous Measurement of Striatal Dopamine and Hydrogen Peroxide Transients Associated with L-DOPA Induced Rotation in Hemiparkinsonian Rats
por: Wilson, Leslie R., et al.
Publicado: (2021)

The L-DOPA/Dopamine Pathway Transgenerationally Regulates Cuticular Melanization in the Pea Aphid Acyrthosiphon pisum
por: Zhang, Yi, et al.
Publicado: (2020)

Corrigendum: Combination Treatment of Icariin and L-DOPA Against 6-OHDA-Lesioned Dopamine Neurotoxicity
por: Lu, Di-Sheng, et al.
Publicado: (2020)

Gypenosides ameliorate memory deficits in MPTP-lesioned mouse model of Parkinson’s disease treated with L-DOPA
por: Zhao, Ting Ting, et al.
Publicado: (2017)

L-DOPA
por: Hornykiewicz, Oleh
Publicado: (2017)

Gypenosides attenuate the development of L-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned rat model of Parkinson’s disease
por: Shin, Keon Sung, et al.
Publicado: (2015)

CoPc and CoPcF(16) on gold: Site-specific charge-transfer processes
por: Petraki, Fotini, et al.
Publicado: (2014)

Genetic Variation in the Human Brain Dopamine System Influences Motor Learning and Its Modulation by L-Dopa
por: Pearson-Fuhrhop, Kristin M., et al.
Publicado: (2013)

The Dopamine D5 receptor contributes to activation of cholinergic interneurons during L-DOPA induced dyskinesia
por: Castello, Julia, et al.
Publicado: (2020)

Oral berberine improves brain dopa/dopamine levels to ameliorate Parkinson’s disease by regulating gut microbiota
por: Wang, Yan, et al.
Publicado: (2021)

The Relationship Between Frontostriatal Connectivity and Striatal Dopamine Function in Schizophrenia: An (18)F-DOPA PET and Diffusion Tensor Imaging Study in Treatment Responsive and Resistant Patients
por: Shin, Sangho, et al.
Publicado: (2022)

Fucoxanthin Prevents Long-Term Administration l-DOPA-Induced Neurotoxicity through the ERK/JNK-c-Jun System in 6-OHDA-Lesioned Mice and PC12 Cells
por: Liu, Jingwangwei, et al.
Publicado: (2022)

Vincamine Alleviates Amyloid-β 25–35 Peptides-induced Cytotoxicity in PC12 Cells
por: Han, Jianfeng, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_in904u3bd3glgm2ir92dk3n0ie