Small-animal SPECT/CT imaging of cancer xenografts and pulmonary fibrosis using a (99m)Tc-labeled integrin αvβ6-targeting cyclic peptide with improved in vivo stability

ABSTRACT: Integrin αvβ6 is expressed at an undetectable level in normal tissues, but is remarkably upregulated during many pathological processes, especially in cancer and fibrosis. Noninvasive imaging of integrin αvβ6 expression using a radiotracer with favorable in vivo pharmacokinetics would faci...

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Detalles Bibliográficos
Autores principales: Liu, Hao, Gao, Liquan, Yu, Xinhe, Zhong, Lijun, Shi, Jiyun, Jia, Bing, Li, Nan, Liu, Zhaofei, Wang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245143/
https://www.ncbi.nlm.nih.gov/pubmed/30533490
http://dx.doi.org/10.1007/s41048-018-0071-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245143/
https://www.ncbi.nlm.nih.gov/pubmed/30533490
http://dx.doi.org/10.1007/s41048-018-0071-1

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