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Synthesis of Polynucleotide Analogs Containing a Polyvinyl Alcohol Backbone

Water soluble homo-base polynucleotide analogues were synthesized in which polyvinyl alcohol and partially phosphonated polyvinyl alcohol constituted the backbones, onto which were grafted uracil or adenine via 1,3-dioxane spacers formed by acetal formation with the 1,3-diol moieties in PVA. The res...

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Detalles Bibliográficos
Autores principales: Yu, Qiang, Carlsen, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245193/
https://www.ncbi.nlm.nih.gov/pubmed/18463571
http://dx.doi.org/10.3390/molecules13030701