Syntaxin 4 Expression in Pancreatic β-Cells Promotes Islet Function and Protects Functional β-Cell Mass

Syntaxin 4 (Stx4) enrichment in human and mouse islet grafts improves the success of transplants in reversing streptozotocin (STZ)-induced diabetes in mice, although the underlying molecular mechanisms remain elusive. Toward a further understanding of this, human islets and inducible transgenic mice...

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Detalles Bibliográficos
Autores principales: Oh, Eunjin, Ahn, Miwon, Afelik, Solomon, Becker, Thomas C., Roep, Bart O., Thurmond, Debbie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2018
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245223/
https://www.ncbi.nlm.nih.gov/pubmed/30305365
http://dx.doi.org/10.2337/db18-0259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245223/
https://www.ncbi.nlm.nih.gov/pubmed/30305365
http://dx.doi.org/10.2337/db18-0259

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