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Syntaxin 4 Expression in Pancreatic β-Cells Promotes Islet Function and Protects Functional β-Cell Mass
Syntaxin 4 (Stx4) enrichment in human and mouse islet grafts improves the success of transplants in reversing streptozotocin (STZ)-induced diabetes in mice, although the underlying molecular mechanisms remain elusive. Toward a further understanding of this, human islets and inducible transgenic mice...
Autores principales: | Oh, Eunjin, Ahn, Miwon, Afelik, Solomon, Becker, Thomas C., Roep, Bart O., Thurmond, Debbie C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245223/ https://www.ncbi.nlm.nih.gov/pubmed/30305365 http://dx.doi.org/10.2337/db18-0259 |
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