CoMFA, CoMSIA and Eigenvalue Analysis on Dibenzodioxepinone and Dibenzodioxocinone Derivatives as Cholesteryl Ester Transfer Protein Inhibitors

CoMFA, CoMSIA and eigenvalue analysis (EVA) were performed to study the structural features of 61 diverse dibenzodioxepinone and dibenzodioxocinone analogues to probe cholesteryl ester transfer protein (CETP) inhibitory activity. Three methods yielded statistically significant models upon assessment...

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Detalles Bibliográficos
Autores principales: Xiong, Xu-qiong, Zhao, Dong-mei, Bu, Peng-fei, Liu, Yang, Ren, Jin-hong, Wang, Jian, Cheng, Mao-sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245342/
https://www.ncbi.nlm.nih.gov/pubmed/18794787
http://dx.doi.org/10.3390/molecules13081822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245342/
https://www.ncbi.nlm.nih.gov/pubmed/18794787
http://dx.doi.org/10.3390/molecules13081822

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