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Unexpected Reduction of Ethyl 3-Phenylquinoxaline-2-carboxylate 1,4-Di-N-oxide Derivatives by Amines(†)

The unexpected tendency of amines and functionalized hydrazines to reduce ethyl 3-phenylquinoxaline-2-carboxylate 1,4-di-N-oxide (1) to afford a quinoxaline 1c and mono-oxide quinoxalines 1a and 1b is described. The experimental conditions were standardized to the use of two equivalents of amine in...

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Detalles Bibliográficos
Autores principales: Lima, Lidia M., Vicente, Esther, Solano, Beatriz, Pérez-Silanes, Silvia, Aldana, Ignacio, Monge, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245414/
https://www.ncbi.nlm.nih.gov/pubmed/18259131
http://dx.doi.org/10.3390/molecules13010078