Overexpression of the Pdx-1 Homeodomain Transcription Factor Impairs Glucose Metabolism in Cultured Rat Hepatocytes

The Pdx-1 transcription factor plays crucial functions both during pancreas development and in the adult β cells. Previous studies have indicated that ectopic Pdx-1 expression in liver or intestinal primary and immortalized cells is sufficient to promote activation of insulin gene expression. This w...

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Detalles Bibliográficos
Autores principales: Pillich, Rudolf Tito, Scarsella, Gianfranco, Risuleo, Gianfranco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245418/
https://www.ncbi.nlm.nih.gov/pubmed/18971862
http://dx.doi.org/10.3390/molecules13102659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245418/
https://www.ncbi.nlm.nih.gov/pubmed/18971862
http://dx.doi.org/10.3390/molecules13102659

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