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Cholesterylbutyrate Solid Lipid Nanoparticles as a Butyric Acid Prodrug

Cholesterylbutyrate (Chol-but) was chosen as a prodrug of butyric acid. Butyrate is not often used in vivo because its half-life is very short and therefore too large amounts of the drug would be necessary for its efficacy. In the last few years butyric acid's anti-inflammatory properties and i...

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Detalles Bibliográficos
Autores principales: Brioschi, Andrea, Zara, Gian Paolo, Calderoni, Sara, Gasco, Maria Rosa, Mauro, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245427/
https://www.ncbi.nlm.nih.gov/pubmed/18305415
http://dx.doi.org/10.3390/molecules13020230