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Synthesis and Antimalarial Evaluation of Cyclicβ-Amino Acid-Containing Dipeptides

This paper describes an efficient synthesis and the antiparasitic evaluation of cyclic β-amino acid-containing dipeptides 3.1-3.6 and 4.1-4.5. The antimalarial properties of all these dipeptides have been evaluated in vitro against Plasmodium falciparum and in vivo against Plasmodium berghai. Compou...

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Detalles Bibliográficos
Autores principales: Sathe, Manisha, Thavaselvam, Duraipandian, Srivastava, Ashish Kumar, Kaushik, Mahabir Parshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245466/
https://www.ncbi.nlm.nih.gov/pubmed/18305429
http://dx.doi.org/10.3390/molecules13020432