Cargando…

Design, Synthesis and Applications of Hyaluronic Acid-Paclitaxel Bioconjugates†

Paclitaxel (1a), a well known antitumor agent adopted mainly for the treatment of breast and ovarian cancer, suffers from significant disadvantages such as low solubility, certain toxicity and specific drug-resistance of some tumor cells. To overcome these problems extensive research has been carrie...

Descripción completa

Detalles Bibliográficos
Autores principales: Leonelli, Francesca, La Bella, Angela, Migneco, Luisa Maria, Bettolo, Rinaldo Marini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245481/
https://www.ncbi.nlm.nih.gov/pubmed/18305424
http://dx.doi.org/10.3390/molecules13020360