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Design, Synthesis and Applications of Hyaluronic Acid-Paclitaxel Bioconjugates†
Paclitaxel (1a), a well known antitumor agent adopted mainly for the treatment of breast and ovarian cancer, suffers from significant disadvantages such as low solubility, certain toxicity and specific drug-resistance of some tumor cells. To overcome these problems extensive research has been carrie...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245481/ https://www.ncbi.nlm.nih.gov/pubmed/18305424 http://dx.doi.org/10.3390/molecules13020360 |