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Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish

Development and function of tissues and organs are powered by the activity of mitochondria. In humans, inherited genetic mutations that lead to progressive mitochondrial pathology often manifest during infancy and can lead to death, reflecting the indispensable nature of mitochondrial biogenesis and...

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Detalles Bibliográficos
Autores principales: Sokol, Anna M., Uszczynska-Ratajczak, Barbara, Collins, Michelle M., Bazala, Michal, Topf, Ulrike, Lundegaard, Pia R., Sugunan, Sreedevi, Guenther, Stefan, Kuenne, Carsten, Graumann, Johannes, Chan, Sherine S. L., Stainier, Didier Y. R., Chacinska, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245507/
https://www.ncbi.nlm.nih.gov/pubmed/30457989
http://dx.doi.org/10.1371/journal.pgen.1007743