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Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish
Development and function of tissues and organs are powered by the activity of mitochondria. In humans, inherited genetic mutations that lead to progressive mitochondrial pathology often manifest during infancy and can lead to death, reflecting the indispensable nature of mitochondrial biogenesis and...
Autores principales: | Sokol, Anna M., Uszczynska-Ratajczak, Barbara, Collins, Michelle M., Bazala, Michal, Topf, Ulrike, Lundegaard, Pia R., Sugunan, Sreedevi, Guenther, Stefan, Kuenne, Carsten, Graumann, Johannes, Chan, Sherine S. L., Stainier, Didier Y. R., Chacinska, Agnieszka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245507/ https://www.ncbi.nlm.nih.gov/pubmed/30457989 http://dx.doi.org/10.1371/journal.pgen.1007743 |
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