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Augmented concentrations of CX(3)CL1 are associated with interstitial lung disease in systemic sclerosis

BACKGROUND: Dysregulation of Fractalkine (CX(3)CL1) and its receptor CX(3)CR1 has been linked to the pathobiology of chronic inflammatory conditions. We explored CX(3)CL1 in systemic sclerosis (SSc) related progressive interstitial lung disease (ILD) and pulmonary hypertension (PH) in two different...

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Detalles Bibliográficos
Autores principales: Hoffmann-Vold, Anna-Maria, Weigt, Stephen Samuel, Palchevskiy, Vyacheslav, Volkmann, Elizabeth, Saggar, Rajan, Li, Ning, Midtvedt, Øyvind, Lund, May Brit, Garen, Torhild, Fishbein, Michael C., Ardehali, Abbas, Ross, David J., Ueland, Thor, Aukrust, Pål, Lynch, Joseph P., Elashoff, Robert M., Molberg, Øyvind, Belperio, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245508/
https://www.ncbi.nlm.nih.gov/pubmed/30457999
http://dx.doi.org/10.1371/journal.pone.0206545