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Structure of paused transcription complex Pol II-DSIF-NELF

Metazoan gene regulation often involves pausing of RNA polymerase II (Pol II) in the promoter-proximal region. Paused Pol II is stabilized by the protein complexes DRB sensitivity-inducing factor (DSIF) and negative elongation factor (NELF). Here we report the cryo-electron microscopy (cryo-EM) stru...

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Detalles Bibliográficos
Autores principales:	Vos, Seychelle M., Farnung, Lucas, Urlaub, Henning, Cramer, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245578/ https://www.ncbi.nlm.nih.gov/pubmed/30135580 http://dx.doi.org/10.1038/s41586-018-0442-2

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