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Suppressed OGT expression inhibits cell proliferation while inducing cell apoptosis in bladder cancer

BACKGROUND: This study aimed to explore hyper-O-linked N-acetylglucosaminylation (O-GlcNAcylation) with an elevation of the expression of O-linked-β-N-acetylglucosamine transferase (OGT) in human bladder cancer. METHODS: Immunohistochemical staining for OGT and O-GlcNAcylation was performed in 20 pa...

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Detalles Bibliográficos
Autores principales: Wang, Longsheng, Chen, Shaojun, Zhang, Ziwei, Zhang, Junfeng, Mao, Shiyu, Zheng, Jiayi, Xuan, Yang, Liu, Mengnan, Cai, Keke, Zhang, Wentao, Guo, Yadong, Zhai, Wei, Yao, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245611/
https://www.ncbi.nlm.nih.gov/pubmed/30453909
http://dx.doi.org/10.1186/s12885-018-5033-y