Deficiency in interleukin-18 promotes differentiation of brown adipose tissue resulting in fat accumulation despite dyslipidemia

BACKGROUND: The cytokine, interleukin-18 (IL-18), was originally identified as an interferon-γ-inducing proinflammatory factor; however, there is increasing evidence suggesting that it has non-immunological effects on physiological functions. We have previously investigated the potential pathophysio...

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Detalles Bibliográficos
Autores principales: Yamanishi, Kyosuke, Maeda, Seishi, Kuwahara-Otani, Sachi, Hashimoto, Takuya, Ikubo, Kaoru, Mukai, Keiichiro, Nakasho, Keiji, Gamachi, Naomi, El-Darawish, Yosif, Li, Wen, Okuzaki, Daisuke, Watanabe, Yuko, Yamanishi, Hiromichi, Okamura, Haruki, Matsunaga, Hisato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245626/
https://www.ncbi.nlm.nih.gov/pubmed/30453990
http://dx.doi.org/10.1186/s12967-018-1684-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245626/
https://www.ncbi.nlm.nih.gov/pubmed/30453990
http://dx.doi.org/10.1186/s12967-018-1684-3

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