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Ambiguity in logic-based models of gene regulatory networks: An integrative multi-perturbation analysis

Most studies of gene regulatory network (GRN) inference have focused extensively on identifying the interaction map of the GRNs. However, in order to predict the cellular behavior, modeling the GRN in terms of logic circuits, i.e., Boolean networks, is necessary. The perturbation techniques, e.g., k...

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Detalles Bibliográficos
Autores principales: Alizad-Rahvar, Amir Reza, Sadeghi, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245684/
https://www.ncbi.nlm.nih.gov/pubmed/30458000
http://dx.doi.org/10.1371/journal.pone.0206976