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Deep learning architectures for prediction of nucleosome positioning from sequences data

BACKGROUND: Nucleosomes are DNA-histone complex, each wrapping about 150 pairs of double-stranded DNA. Their function is fundamental for one of the primary functions of Chromatin i.e. packing the DNA into the nucleus of the Eukaryote cells. Several biological studies have shown that the nucleosome p...

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Detalles Bibliográficos
Autores principales: Di Gangi, Mattia, Lo Bosco, Giosuè, Rizzo, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245688/
https://www.ncbi.nlm.nih.gov/pubmed/30453896
http://dx.doi.org/10.1186/s12859-018-2386-9