Loss of DNA methylation is related to increased expression of miR-21 and miR-146b in papillary thyroid carcinoma

BACKGROUND: DNA methylation in miRNA genes has been reported as a mechanism that may cause dysregulation of mature miRNAs and consequently impact the gene expression. This mechanism is largely unstudied in papillary thyroid carcinomas (PTC). METHODS: To identify differentially methylated miRNA-encod...

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Detalles Bibliográficos
Autores principales: Ortiz, Isabella Maria Dias Payão, Barros-Filho, Mateus Camargo, dos Reis, Mariana Bisarro, Beltrami, Caroline Moraes, Marchi, Fabio Albuquerque, Kuasne, Hellen, do Canto, Luísa Matos, de Mello, Julia Bette Homem, Abildgaard, Cecilie, Pinto, Clóvis Antônio Lopes, Kowalski, Luiz Paulo, Rogatto, Silvia Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245861/
https://www.ncbi.nlm.nih.gov/pubmed/30454026
http://dx.doi.org/10.1186/s13148-018-0579-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245861/
https://www.ncbi.nlm.nih.gov/pubmed/30454026
http://dx.doi.org/10.1186/s13148-018-0579-8

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