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Increased activated regulatory T cell subsets and aging Treg-like cells in multiple myeloma and monoclonal gammopathy of undetermined significance: a case control study
BACKGROUND: Accumulating evidence have indicated that regulatory T cells (Tregs) play an essential role in T cell-mediated immune response and development of multiple myeloma (MM). CD4(+)FoxP3(+) T cells are composed of three phenotypically and functionally distinct subpopulations: CD45RA(+)FoxP3(lo...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245875/ https://www.ncbi.nlm.nih.gov/pubmed/30479566 http://dx.doi.org/10.1186/s12935-018-0687-8 |