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Increased activated regulatory T cell subsets and aging Treg-like cells in multiple myeloma and monoclonal gammopathy of undetermined significance: a case control study

BACKGROUND: Accumulating evidence have indicated that regulatory T cells (Tregs) play an essential role in T cell-mediated immune response and development of multiple myeloma (MM). CD4(+)FoxP3(+) T cells are composed of three phenotypically and functionally distinct subpopulations: CD45RA(+)FoxP3(lo...

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Detalles Bibliográficos
Autores principales: Wang, Ji-nuo, Cao, Xin-xin, Zhao, Ai-lin, Cai, Hao, Wang, Xuan, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245875/
https://www.ncbi.nlm.nih.gov/pubmed/30479566
http://dx.doi.org/10.1186/s12935-018-0687-8