Combined genetic influence of the nicotinic receptor gene cluster CHRNA5/A3/B4 on nicotine dependence

BACKGROUND: The CHRNA5/A3/B4 gene locus is associated with nicotine dependence and other smoking related disorders. While the non-synonymous CHRNA5 variant rs16969968 appears to be the main risk factor, linkage disequilibrium (LD) bins in the gene cluster carry frequent variants that regulate expres...

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Detalles Bibliográficos
Autores principales: Lee, Sung-Ha, Ahn, Woo-Young, Seweryn, Michał, Sadee, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245894/
https://www.ncbi.nlm.nih.gov/pubmed/30453884
http://dx.doi.org/10.1186/s12864-018-5219-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245894/
https://www.ncbi.nlm.nih.gov/pubmed/30453884
http://dx.doi.org/10.1186/s12864-018-5219-3

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