Cargando…

Combined genetic influence of the nicotinic receptor gene cluster CHRNA5/A3/B4 on nicotine dependence

BACKGROUND: The CHRNA5/A3/B4 gene locus is associated with nicotine dependence and other smoking related disorders. While the non-synonymous CHRNA5 variant rs16969968 appears to be the main risk factor, linkage disequilibrium (LD) bins in the gene cluster carry frequent variants that regulate expres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Sung-Ha, Ahn, Woo-Young, Seweryn, Michał, Sadee, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245894/ https://www.ncbi.nlm.nih.gov/pubmed/30453884 http://dx.doi.org/10.1186/s12864-018-5219-3

Ejemplares similares

Association Between CHRNA3 and CHRNA5 Nicotine Receptor Subunit Gene Variants and Nicotine Dependence in an Isolated Populationof Kashubians in Poland
por: Kita-Milczarska, Karolina, et al.
Publicado: (2016)

O015. Evaluation of the genetic polymorphism of the α3 (CHRNA3) and α5 (CHRNA5) nicotinic receptor subunits, in patients with cluster headache
por: Cainazzo, Maria Michela, et al.
Publicado: (2015)

Association of Polymorphism CHRNA5 and CHRNA3 Gene in People Addicted to Nicotine
por: Chmielowiec, Krzysztof, et al.
Publicado: (2022)

Financial and Psychological Risk Attitudes Associated with Two Single Nucleotide Polymorphisms in the Nicotine Receptor (CHRNA4) Gene
por: Roe, Brian E., et al.
Publicado: (2009)

Gene variance in the nicotinic receptor cluster (CHRNA5‐CHRNA3‐CHRNB4) predicts death from cardiopulmonary disease and cancer in smokers
por: Halldén, S., et al.
Publicado: (2015)

Genetic Modifiers of Oral Nicotine Consumption in Chrna5 Null Mutant Mice
por: Meyers, Erin, et al.
Publicado: (2021)

Nicotinic Receptor Gene CHRNA4 Interacts with Processing Load in Attention
por: Espeseth, Thomas, et al.
Publicado: (2010)

Significant association of the CHRNB3-CHRNA6 gene cluster with nicotine dependence in the Chinese Han population
por: Wen, Li, et al.
Publicado: (2017)

CHRNA5 rs16969968 and CHRNA3 rs578776 polymorphisms are associated with multiple nicotine dependence phenotypes in Bangladeshi smokers
por: Chaity, Nusrat Islam, et al.
Publicado: (2022)

Smoking Interacts With CHRNA5, a Nicotinic Acetylcholine Receptor Subunit Gene, to Influence the Risk of IBD-Related Surgery
por: Cushing, Kelly C, et al.
Publicado: (2018)

Genetic influences on nicotinic α5 receptor (CHRNA5) CpG methylation and mRNA expression in brain and adipose tissue
por: Ramsay, Jessica E., et al.
Publicado: (2015)

Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5–CHRNA3–CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight
por: Tyrrell, Jessica, et al.
Publicado: (2012)

Genetic Association Study of the Alpha 7 Nicotinic Receptor (CHRNA7) with the Development of Schizophrenia and Bipolar Disorder in Korean Population
por: Joo, Eun-Jeong, et al.
Publicado: (2010)

Genetic Association of CHRNB3 and CHRNA6 Gene Polymorphisms with Nicotine Dependence Syndrome Scale in Korean Population
por: Won, Wang-Youn, et al.
Publicado: (2014)

A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5–CHRNA3–CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy
por: Freathy, Rachel M., et al.
Publicado: (2009)

Crucial roles of the CHRNB3–CHRNA6 gene cluster on chromosome 8 in nicotine dependence: update and subjects for future research
por: Wen, L, et al.
Publicado: (2016)

Association of the CHRNA4 Neuronal Nicotinic Receptor Subunit Gene with Frequency of Binge Drinking in Young Adults
por: Coon, Hilary, et al.
Publicado: (2014)

Association of the Nicotinic Receptor α7 Subunit Gene (CHRNA7) with Schizophrenia and Visual Backward Masking
por: Bakanidze, George, et al.
Publicado: (2013)

Association and cis-mQTL analysis of variants in CHRNA3-A5, CHRNA7, CHRNB2, and CHRNB4 in relation to nicotine dependence in a Chinese Han population
por: Liu, Qiang, et al.
Publicado: (2018)

Genetic influence of dopamine receptor, dopamine transporter, and nicotine metabolism on smoking cessation and nicotine dependence in a Japanese population
por: Ohmoto, Masanori, et al.
Publicado: (2014)

Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence
por: Hancock, D B, et al.
Publicado: (2015)

Replicated Risk Nicotinic Cholinergic Receptor Genes for Nicotine Dependence
por: Zuo, Lingjun, et al.
Publicado: (2016)

Increased nicotine response in iPSC-derived human neurons carrying the CHRNA5 N398 allele
por: Oni, Eileen N., et al.
Publicado: (2016)

Do nicotine dependence influencing and non-influencing behaviors have an association with high nicotine dependence in smokers?
por: Chen, Zhongbo, et al.
Publicado: (2021)

Four SNPs in the CHRNA3/5 Alpha-Neuronal Nicotinic Acetylcholine Receptor Subunit Locus Are Associated with COPD Risk Based on Meta-Analyses
por: Cui, Kai, et al.
Publicado: (2014)

Genetic Influences on Smoking Behavior and Nicotine Dependence: a Review
por: Yoshimasu, Kouichi, et al.
Publicado: (2007)

Neuronal Nicotinic Acetylcholine Receptors: Common Molecular Substrates of Nicotine and Alcohol Dependence
por: Hendrickson, Linzy M., et al.
Publicado: (2013)

The submembrane machinery for nicotinic acetylcholine receptor clustering
Publicado: (1991)

Role of Nicotine Dependence on the Relationship between Variants in the Nicotinic Receptor Genes and Risk of Lung Adenocarcinoma
por: Tseng, Tung-Sung, et al.
Publicado: (2014)

A Candidate Gene Approach Identifies the CHRNA5-A3-B4 Region as a Risk Factor for Age-Dependent Nicotine Addiction
por: Weiss, Robert B., et al.
Publicado: (2008)

A Complex Interplay between Personality Domains, Marital Status and a Variant in CHRNA5 on the Risks of Cocaine, Nicotine Dependences and Cocaine-Induced Paranoia
por: Zayats, Tetyana, et al.
Publicado: (2013)

Sex- and Genotype-Dependent Nicotine-Induced Behaviors in Adolescent Rats with a Human Polymorphism (rs2304297) in the 3′-UTR of the CHRNA6 Gene
por: Cardenas, Anjelica, et al.
Publicado: (2022)

Cholinergic Receptor Nicotinic Alpha 5 (CHRNA5) RNAi is associated with cell cycle inhibition, apoptosis, DNA damage response and drug sensitivity in breast cancer
por: Cingir Koker, Sahika, et al.
Publicado: (2018)

Multiethnic Prediction of Nicotine Biomarkers and Association With Nicotine Dependence
por: Bergen, Andrew W, et al.
Publicado: (2021)

Hippocampal changes produced by overexpression of the human CHRNA5/A3/B4 gene cluster may underlie cognitive deficits rescued by nicotine in transgenic mice
por: Molas, Susanna, et al.
Publicado: (2014)

Endogenous CHRNA7-ligand SLURP1 as a potential tumor suppressor and anti-nicotinic factor in pancreatic cancer
por: Throm, Verena M., et al.
Publicado: (2018)

Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans
por: Walsh, Kyle M., et al.
Publicado: (2012)

Habenular α5* nicotinic receptor signaling controls nicotine intake
por: Fowler, Christie D., et al.
Publicado: (2011)

Epidemiology, radiology, and genetics of nicotine dependence in COPD
por: Kim, Deog Kyeom, et al.
Publicado: (2011)

Genetic Relationship between Schizophrenia and Nicotine Dependence
por: Chen, Jingchun, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ok8na8p628u8s16fbe4j0sloae