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Metabolite differences between glutamate carboxypeptidase II gene knockout mice and their wild-type littermates after traumatic brain injury: a 7-tesla (1)H-MRS study

BACKGROUND: Traumatic brain injury (TBI) is a complex condition and remains a prominent public and medical health issue in individuals of all ages. A rapid increase in extracellular glutamate occurs after TBI, leading to glutamate-induced excitotoxicity, which causes neuronal damage and further func...

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Detalles Bibliográficos
Autores principales: Wu, Wenbo, Xu, Siyi, Wang, Jialin, Zhang, Kuiming, Zhang, Mingkun, Cao, Yang, Ren, Hongqing, Zheng, Deyou, Zhong, Chunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245916/
https://www.ncbi.nlm.nih.gov/pubmed/30458729
http://dx.doi.org/10.1186/s12868-018-0473-5