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m(6)A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer

N(6)-methyladenosine (m(6)A) mRNA methylation is a gene regulatory mechanism affecting cell differentiation and proliferation in development and cancer. To study the roles of m(6)A mRNA methylation in cell proliferation and tumorigenicity, we investigated human endometrial cancer in which a hotspot...

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Detalles Bibliográficos
Autores principales: Liu, Jun, Eckert, Mark A, Harada, Bryan T, Liu, Song-Mei, Lu, Zhike, Yu, Kangkang, Tienda, Samantha M, Chryplewicz, Agnieszka, Zhu, Allen C, Yang, Ying, Huang, Jing-Tao, Chen, Shao-Min, Xu, Zhi-Gao, Leng, Xiao-Hua, Yu, Xue-Chen, Cao, Jie, Zhang, Zezhou, Liu, Jianzhao, Lengyel, Ernst, He, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245953/
https://www.ncbi.nlm.nih.gov/pubmed/30154548
http://dx.doi.org/10.1038/s41556-018-0174-4