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KMgene: a unified R package for gene-based association analysis for complex traits

SUMMARY: In this report, we introduce an R package KMgene for performing gene-based association tests for familial, multivariate or longitudinal traits using kernel machine (KM) regression under a generalized linear mixed model framework. Extensive simulations were performed to evaluate the validity...

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Detalles Bibliográficos
Autores principales: Yan, Qi, Fang, Zhou, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246171/
https://www.ncbi.nlm.nih.gov/pubmed/29438558
http://dx.doi.org/10.1093/bioinformatics/bty066